Our mission is to support the community of researchers dedicated to improving early detection of cancer. This website is a repository of published scientific papers and news as well as a forum for discussion and debate about advancements and issues in the field of cancer early detection. We hope to foster communication among scientists in all the diverse disciplines that contribute to this field.
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Kurman et al. have published a review in the American Journal of Obstetrics and Gynecology arguing that aggressive ovarian cancer is often never confined to the ovary, and thus early detection methods that focus on finding low-stage localized tumors will miss these more common, more deadly cancers. They recommend refocusing research efforts from detecting early stage ovarian cancers to detecting aggressive but small volume cancers. Read the paper and tell us if you are convinced.
| Title | Authors | Published | Views | Comments |
|---|---|---|---|---|
| Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of | Kurman, RJ; Visvanathan, K; Roden, R; Wu, TC; Shih, IeM | 2008 | 128 | 1 |
| Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. | Majewski, T; Lee, S; Jeong, J; Yoon, DS; Kram, A; Kim, MS; Tuziak, T; Bondaruk, J; Lee, S; Park, WS; Tang, KS; Chung, W; Shen, L; Ahmed, SS; Johnston, DA; Grossman, HB; Dinney, CP; Zhou, JH; Harris, RA; Snyder, C; Filipek, S; Narod, SA; Watson, P; Lynch, HT; Gazdar, A; Bar-Eli, M; Wu, XF; McConkey, DJ; Baggerly, K; Issa, JP; Benedict, WF; Scherer, SE; Czerniak, B | 2008 | 118 | 0 |
| Genetic and biologic evidence that implicates a gene in aggressive prostate cancer. | Hsieh JT, Karam JA, Min W | 2007 | 104 | 0 |
| The cancer biomarker problem. | Sawyers, CL | 2008 | 93 | 0 |
| Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express | Jen, CH; Yang, TP; Tung, CY; Su, SH; Lin, CH; Hsu, MT; Wang, HW | 2008 | 86 | 0 |
| 2-deoxy-2-[F-18]fluoro-D-glucose accumulation in ovarian carcinoma cell lines. | Lutz AM, Ray P, Willmann JK, Drescher C, Gambhir SS. | 2007 | 86 | 0 |
| Use of an immunoaffinity-mass spectrometry based approach for the quantification of protein biomarkers from serum samples of lun | Nicol, GR; Han, M; Kim, J; Birse, CE; Brand, E; Nguyen, A; Mesri, M; Fitzhugh, W; Kaminker, P; Moore, PA; Ruben, SM; He, T | 2008 | 81 | 0 |
| Combining Multiple Biomarker Models in Logistic Regression. | Yuan, Z; Ghosh, D | 2008 | 81 | 0 |
| Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. | Leng, S; Stidley, CA; Willink, R; Bernauer, A; Do, K; Picchi, MA; Sheng, X; Frasco, MA; Van Den Berg, D; Gilliland, FD; Zima, C; Crowell, RE; Belinsky, SA | 2008 | 75 | 0 |
| Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neopl | Moniaux, N; Chakraborty, S; Yalniz, M; Gonzalez, J; Shostrom, VK; Standop, J; Lele, SM; Ouellette, M; Pour, PM; Sasson, AR; Brand, RE; Hollingsworth, MA; Jain, M; Batra, SK | 2008 | 74 | 0 |